WebMay 13, 2011 · Invitro floating ability: 100 mg of microspheres were placed in 0.1 N Hcl containing 0.02% tween 20 and stirred at 100 rpm. The layer of buoynant microspheres was filtered at 1, 2, 4 and 6 hrs. The collected microspheres were dried in dessicator over night. %floating microspheres = (final wt/initial wt) × 100. Table 1 Composition of … WebThe objective of the present study was to develop Glimepiride floating microspheres in order to achieve an extended retention in the upper GIT, which enhances the absorption and improves the bioavailability. The microspheres were prepared by emulsion solvent diffusion-evaporation method using different ratios of rate
FORMULATION AND EVALUATION OF FLOATING MICROSPHERES …
New applications for microspheres are discovered every day. Below are just a few: • Assay - Coated microspheres provide measuring tool in biology and drug research • Buoyancy - Hollow microspheres are used to decrease material density in plastics (glass and polymer), neutrally-buoyant microspheres are frequently used for fluid flow visualization. WebMicrospheres are spherical, free-flowing, organic/inorganic with a size range of 1–1000 μm in diameter in which bioactive molecules, as well as drugs, can be encapsulated. … grainfather stainless steel fermenter
Development and Characterization of Rifampicin Loaded Floating Microspheres
WebDec 1, 2012 · The formulated floating microspheres were characterized for their micromeritic properties, surface morphology by SEM, in-vitro buoyancy studies, percentage drug entrapment efficiency and in-vitro drug release studies. Optimization studies were carried out by taking organic phase volume and drug: polymer ratio as independent … WebMicrosphere. True density of HGMs can most conveniently be measured using gas pycnometry, which is a common analytical technique that uses a gas displacement method to measure volume accurately. ... Floating microspheres that are meant to release the drugs loaded in them in gastric content. Radioactive particles which are used for the ... grainfather used