WebThe most common adverse effect of statins is myalgia (a class side effect), without creatine kinase (CK) elevations; rhabdomyolysis (CK >10000 IU/L or CK >10 x ULN [upper limit of normal] with serum creatinine elevation) is a far less common side effect. Webfor the purposes of this guidance, intolerance to initial statin therapy should be defined as the presence of clinically significant adverse effects from statin therapy that are …
primary prevention - high cholesterol - General Practice notebook
WebFeb 13, 2024 · Statins shouldn't be taken if you have severe liver disease or blood tests suggest that your liver may not be working properly. This is because statins can affect your liver, and this is more likely to cause serious problems if … Webtheir advice for monitoring and management of SAMS; their advice1,8, and ours9, is summarised in Table 1. NICE recommends that a baseline CK prior to statin initiation is only necessary if there is pre-existing muscle pain and to recheck this only if the patient reports SAMS. If the CK is <3x ULN, advise statin continuation. If it is >5x ULN huawei watch 3 pro review
statins (starting/monitoring therapy) - General Practice notebook
WebCheck creatine kinase (CK) only if muscle aches/weakness. If statin-intolerance, address (Table 10). If lipids do not decrease as expected: address adherence, reinforce lifestyle modifications, and ... elevated ALT, so as not to have to stop statins. Consider monitoring annually for stability if baseline LFTs are abnormal. Webmeasure total cholesterol, HDL cholesterol and non-HDL cholesterol in all people who have been started on high-intensity statin treatment at 3 months of treatment and aim for a greater than 40% reduction in non-HDL cholesterol. If a greater than 40% reduction in non-HDL cholesterol is not achieved: discuss adherence and timing of dose WebMar 19, 2024 · For a short explanation of why the committee made these recommendations and how they might affect practice, see the rationale and impact section on monitoring the risk of rupture. Full details of the evidence and the committee's discussion are in evidence review D: monitoring for abdominal aortic aneurysm expansion and risk of rupture. hogan mobile recharge voucher